APS can offer small to large scale (milligram to gram quantities) production of hybridomas created as part of the custom monoclonal antibody project, or from customer owned hybridomas. Prior to the scale up, hybridomas are evaluated by several quality control points and extra subcloning is performed to ensure monoclonality and stability.
Phase 0 - (1-4 weeks) Preparation of hybridoma for scale-up.
Phase 1 - (4-6 weeks) Scale-up of hybridoma with option for serum free media.
Phase 2 - (2 weeks) Antibody purification and characterisation.